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2016 IPO Prospects: Human Longevity Leverages Machine Learning and Analytics to Increase Lifespan

Posted on Thursday, Aug 18th 2016


According to a recent Deloitte report, advances in medical science are leading to an increased life expectancy. In 2014, the average life expectancy globally was 72.3 years and that is expected to grow to 73.3 years by 2019. In 2019, 11% of the total population are expected to be aged more than 65 years. Analysts expect that out of the global health spend of nearly $7 trillion, nearly half of the funds are diverted to making sure that this ageing population continues to live longer. Human Longevity’s Offerings

La Jolla, California-based Human Longevity (HLI) is one player that is successfully integrating genomics and technology to help create the world’s largest and most comprehensive database of whole genome, phenotype, and clinical data that can be used to increase human longevity. The company is focusing on understanding and interpreting the true characteristics embedded in the human genome, taking this genetic code, and translating it into meaningful insights. It believes that it can sequence a person’s DNA and combine it with other clinical tests to identify how long the person will live, and what can be done to extend their life, even before a disease, such as cancer, shows symptoms.

HLI was founded in 2013 by leading scientists J. Craig Venter, Robert Hariri, and Peter H Daimandis. Together, the three visionaries are working on developing and applying large-scale computing and machine learning technologies in the field of medicine. HLI operates Big Data processing centers that are able to integrate machine learning capabilities into genome database to develop new ways of fighting aging related diseases.

Till the end of 2015, HLI was able to sequence around 100,000 genomes annually. It expects to improve computing power to be able to sequence as many as 1 million genomes per year. Its database is enabling pharmaceutical companies, insurers, and healthcare providers to impact healthy living conditions of their end users. For instance, HLI offers exome, genome, and cancer genome sequencing to Discovery Insurance Clients in South Africa and the United Kingdom to help the company develop a behavioral wellness solution for its patrons.

The program’s subscribers are able to get access to tools, knowledge, and incentives to improve their health based on the exome sequencing and analysis customized for them. Additionally, healthcare providers can provide an integrated assessment of health status and potential risks for individuals and families using predictive solutions with focus on cancer analysis, integrated health analysis, newborn screening and rare, undiagnosed diseases.

Human Longevity’s Financials

HLI does not disclose its financials. Its revenue stream includes database licensing to pharmaceutical, biotechnology, and academic organizations. It also earns revenues by providing services such as sequencing and development of advanced diagnostics and therapeutics to its customers.

Its Health Nucleus service charges patients $25,000 in which they get a battery of tests conducted over a day. At the end of the day, the patient is sent home with a small device that measures heart rate for a two-week period. After the completion of these tests, the patient is able to access a 3D view of themselves and are able to get a complete profile of almost one petabyte of medical information. This information can then be used to provide customized medical treatment and healthy lifestyle approaches.

It is venture funded so far with $300 million in investments from investors including Bryan Johnson, Celgene, Daniel Curran, Draper Fisher Jurvetson (DFJ), GE Ventures, Illumina, Synthetic Genomics, and Tan Thay. Its last round of funding was held in April this year when it raised $220 million in a round led by Illumina at a valuation of $1.2 billion. The funding is expected to help HLI expand before it finally goes public. HLI has not disclosed plans of when it will go public.

Very interesting company, with one caveat: I personally do not want to live all that long, so too much increase in life expectancy isn’t something I am personally in favor of. The planet has limited resources, and Artificial Intelligence is driving automation to extremes, such that robots will replace humans in large swathes of the economy. Both economically and environmentally, longevity extension is something I am against, and this, once again, is another scientific discipline where I am compelled to ask the question, Just because we can, does it mean we should?

Photo Credit: Reginald Pentinio/ 

This segment is a part in the series : 2016 IPO Prospects

. Airbnb Sees Skyrocketing Valuations
. Actifio Looks Ready
. AppDynamics May Sustain Unicorn Valuation
. Automattic Needs to Justify Valuation
. Avant Will Have to Wait and Watch
. BuzzFeed Feeds on Native Advertising
. Coupa Manages Expenses Expertly
. Datto Bootstrapped First, Raised Money Later
. Is Uber Ready to Ride the Stock Market?
. Overfunded Domo Looks Promising
. Houzz May Unveil The Curtains
. DocuSign Looks Ready to Sign Up
. Illumio Rides On Security Trend
. Appears Ready to List
. Okta Prepares to Reveal Public Identity
. Palantir Wants to Stay Private
. Nutanix Files for IPO
. Medallia Bootstrapped First, Raised Money Later
. Slack Prepares to Communicate with the Market
. Twilio Expected to go Public Soon
. Snapchat Needs to Up Monetization ASAP
. Zscaler Sets IPO as a Long-Term Goal
. Warby Parker Should Look Before Leaping
. MuleSoft is a Unicorn, but Detailed Financials Remain Unknown
. Apttus Bootstrapped First, Raised Money Later
. Fanatics Expanding Its Playing Field
. Pinterest Finally Sees Revenues, But are they Enough?
. Tanium Bootstrapped First, Raised Money Later
. ironSource Strengthening its Revenue Generating Capabilities
. Anaplan Getting Ready to Go Public
. SecureWorks is Ready to List
. IPO-Ready Cloudera Wants to Wait and Watch
. HelloFresh Puts its IPO Plans on Hold
. Is Stripe Lining up Next?
. Qualtrics Bootstrapped First, Raised Money Later
. Skyscanner Bootstraps First from Scotland, Raises Money Later from Sequoia
. SurveyMonkey Will Likely Wait
. The Honest Company Makes the Online to Offline Model Work
. NantHealth Testing the IPO Markets, Yet Again
. BigCommerce Prepares to List
. Bloom Energy Likely to Stay Private
. Avast Software Preparing for a Listing, Yet Again
. Gusto Expands Beyond Payroll Processing
. InMobi May Have Missed the Bus
. Glassdoor Gearing up to go Public
. Human Longevity Leverages Machine Learning and Analytics to Increase Lifespan
. Blue Apron Cooking up an IPO
. Optiv Grows Inorganically
. Uber Eyeing Self-Driving
. The Trade Desk Files to List
. Deliveroo Delivers its Way to the Bank
. Selfie App Meitu Files to List on HKSE
. Apptio Files Despite Reduced Valuation and Mounting Losses
. Snap Snaps out of Chat Business to Justify Valuation
. From Bootstrapping to IPO, BlackLine Shows the Way

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